ANSC-6119 Introductory Population Genetics 2(1-1)

This is the course of under graduate level about the population genetics. Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure. Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, lab, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart today from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and adaptive dynamics, is its emphasis on genetic phenomena. The course provides the students theoretical and practical knowledge of the population genetics. Students practically and theoretically trained for getting better genotype in the next generation. This course will help students gain an insight into the latest techniques for livestock improvement through genetics.

Theory

Gene and genotypic frequency; Hardy-Weinberg law; forces affecting gene frequency and composition of population,  Quantitative characters and their inheritance;  measures of central tendency and dispersion for quantitative traits; Basic theorems of additively of variance, regression and correlation concepts; Nature and causes of variation in quantitative traits and partitioning of hereditary variance; Concepts of heritability and repeatability and methods of their estimation; Genetic and phenotypic correlations; Genetic basis and causes of variation, lethal factor, Genetic disorders and genetic resistance to diseases, Genetic constitution of population, Population-Genetic properties of population.

Practical

Exercises on gene and genotypic frequencies in random mating populations.  Exercises on the estimation of heritabilities, repeatabilities and genetic correlation from given data. Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

WEEK

Topics and Readings

Book Page No.

Weeks

Topic

 
  1.  

Gene and genotypic frequency. Exercises on gene and genotypic frequencies in random mating populations.

Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (133-138)

2

Hardy-Weinberg law; forces affecting gene frequency and composition of population. Exercises on gene and genotypic frequencies in random mating populations.

Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (139-151)

3

Forces affecting gene frequency and composition of populationNumerical exercises on the estimation of various statistical parameters and hypothesis testing using computers

. Principles of Genetice, By Gardner, Simmons, Snustad, page (553-557)

4

Quantitative characters and their inheritance. Numerical exercises on the estimation of various statistical parameters and hypothesis testing using computers.

 

Principles of Genetic, By Gardner, Simmons, Snustad,

 page (553-557)

5

Quantitative characters and their inheritance. Numerical exercises on the estimation of various statistical parameters and hypothesis testing using computers.

Internet , Lasely .Animal Husbandry S Iqbal Shah,

6

measures of central tendency and dispersion for quantitative traits. Numerical exercises on the estimation of various statistical parameters and hypothesis testing using computers.

Internet , Lasely .Animal Husbandry S Iqbal Shah,

7

Basic theorems of additively of variance. Numerical exercises on the estimation of various statistical parameters and hypothesis testing using

A Text Book of  Animal Genetics, By P. Kanakaraj, Page (363-367)

8

Basic theorems of additively of variance. Numerical exercises on the estimation of various statistical parameters and hypothesis testing using computers.

A Text Book of  Animal Genetics, By P. Kanakaraj, Page (363-367)

9

Mid Test

 

10

regression and correlation concepts. Exercises on the estimation of heritabilities, repeatabilities and genetic correlation from given data.

 Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (168-175)

11

Nature and causes of variation in quantitative traits and partitioning of hereditary variance. Exercises on the estimation of heritabilities, repeatabilities and genetic correlation from given data.

. Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (162-165)

12

Concepts of  repeatability and methods of their estimation. Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (170-172)

13

  lethal factor, Genetic disorders and genetic resistance to diseases.Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (170-172)

14

Genetic correlations. Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

Principles of Genetics and animal breeding, By FH Khan, Ashok Singh, Page (173-175)

15

Genetic constitution of population. Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

A Text Book of  Animal Genetics, By P. Kanakaraj, page (393-397)

16

Genetic basis and causes of variation. Case studies for lethal, semi-lethal and other genetic abnormalities in farm animals.

Genetics of Livestock Improvement 4th edition, By John F. Lasley, Page (63-75)

 

 

ASSIGNMENT CRITERIA

 

Sessional: 04

Mid-term: 06

Final Exam: 10

Practical: 20

Other Courses by Ms. Atia Iram