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• Investigation of Reaction Mechanism: Introduction
• Nature of Products and Thermodynamics requirements
• Kinetic requirements of reaction mechanism
• Study of Intermediates: Isolation, Detection and Trapping
• Stereochemical studies towards reaction mechanism
• Isotopic Studies: Isotopic labeling, Isotopic Effect, Isotopic Scrambling
• Addition reactions
• Classification of elimination reactions. E1 vs E2. Syn / anti eliminations
• MID TERM
• E1cB eliminations. Regioselectivity, Pyrolytic Eliminations, Factors affecting eliminations
• Electrophilic and Nucleophilic substitution reactions at aromatic systems
• Aliphatic Nucleophilic substitution reactions (SN1, SN2, SNi, SN1', SN2', SNi')
• Factors affecting Substitution Reactions. Neighbouring group participation
• Active Methylene Compounds
• Claisen reaction, Claisen–Schmidt reaction and Wittig reaction
• Darzen’s glycidic ester synthesis, Reformatsky reaction and Stobbes condensation
• Knovenagel reaction, Mannich reaction and Perkin reaction
• FINAL TERM