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Organic Chemistry-II (CHEM-373)
Claisen reaction, Claisen–Schmidt reaction and Wittig reaction
Claisen reaction, Claisen–Schmidt reaction and Wittig reaction
Claisen reaction, Claisen–Schmidt reaction and Wittig reaction
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Course Material
Investigation of Reaction Mechanism: Introduction
Nature of Products and Thermodynamics requirements
Kinetic requirements of reaction mechanism
Study of Intermediates: Isolation, Detection and Trapping
Stereochemical studies towards reaction mechanism
Isotopic Studies: Isotopic labeling, Isotopic Effect, Isotopic Scrambling
Addition reactions
Classification of elimination reactions. E1 vs E2. Syn / anti eliminations
MID TERM
E1cB eliminations. Regioselectivity, Pyrolytic Eliminations, Factors affecting eliminations
Electrophilic and Nucleophilic substitution reactions at aromatic systems
Aliphatic Nucleophilic substitution reactions (SN1, SN2, SNi, SN1', SN2', SNi')
Factors affecting Substitution Reactions. Neighbouring group participation
Active Methylene Compounds
Claisen reaction, Claisen–Schmidt reaction and Wittig reaction
Darzen’s glycidic ester synthesis, Reformatsky reaction and Stobbes condensation
Knovenagel reaction, Mannich reaction and Perkin reaction
FINAL TERM
Chapters
18
Department
Chemistry
Teacher
Dr. Jamshed Akbar