CHEM-415 ADVANCED SPECTROSCOPY – II (MINOR)

Course Tittle:        ADVANCED SPECTROSCOPY – II (MINOR)

Course Code:        CHEM-415

Credit Hours:        (3+1)

Instructor. DR Yasmeen Gull

email. [email protected]

DESCRIPTION & OBJECTIVES

This course is designed to study the concepts about different advanced spectroscopic techniques. Mass spectrometry is an important field of analysis for known and also for  newly synthsized unknown compunds. Detailed study of mass spectrometer is available in this course. Fluorescence studies is an important tool for structure elucidation, Merits & limitations of X-ray spectroscopy will be shared. This course contains information about Molecular luminescence spectroscopy.

READINGS

  1. Skoog D. and West D.M., Fundamentals of Analytical Chemistry, Holt Reinhart Inc, London. (1996).
  2. Christian G.D., Analytical Chemistry, John Wiley & Sons. (2010).
  3. Harris D.C., Quantitative Chemical Analysis, Freeman, N. Y. (2006).
  4. Douglas A. Skoog, Donald M. West, F. James Holler, Stanley R. Crouch Fundamentals of Analytical Chemistry; 8th ed. Saunders College Publishing, Philadelphia. (2003)

CONTENTS

Mass Spectrometry: Principle of Mass spectroscopy, Instrumentation in details, Quantitative and Qualitative application in analytical chemistry. X-rays Spectroscopy: Nature and production of X-rays, X-rays absorption, X-rays emission, Instrumentation, X-rays fluorescence analysis, Diffraction studies single crystal analysis.

 

WEEKLY LECTURE SCHEDULE

 Week                 Topics                                                                                  Date
1 Mass Spectrometry, Principle of MS, Molecular ion, Base Peak January 13-17, 2020
2 Resolving power and resolution of a Mass Spectrometry, Instrumentation, Sample Inlet System January 20-24, 2020
3 onization Sources, Electron Impact source, Chemical Ionization, Atmospheric pressure ionization sources January 27-31, 2020
4 FAB, Ionization Sources for Inorganic MS,Laser Desorption, MALDI, February 3-7, 2020
5 Mass Analyzer, Magnetic Sector Analyzer, Time of flight Analyzer, February 10-14, 2020
6 Quadrupole Mass Analyzer, February 17-21, 2020
7 Detectors, Electron Multiplier, February 24-28, 2020
8 Faraday cup, Array detector March 2-6, 2020
9 Mid Exam March 9-13,2020
10 Quadrupole Ion Trap March 16-20, 2020
11 Quantitative and Qualitative applications in Analytical Chemistry, Interpretation of mass spectra March 23-27, 2020
12 Structural determination of simple molecules March 30 -April 3, 2020
13 X-ray spectroscopy: Origin of X-ray spectra, Energy Levels in Atoms,Analytical Application of X-Rays April 6-10, 2020
14 Moseley’s law, X-Ray Methods, x-ray absorption process,X-ray fluorescence  (XRF) process April 13-17, 2020
15 The X-ray Diffraction (XRD) process,Sample introduction and handling for surface analysis April 20-24, 2020
16 Analytical applications of XPS,Electron spectroscopy for Chemical Analysis (ESCA): Introduction, Principle April 27- May 01,  2020
17 EDXRF spectrometers: X-Absorption, X-rays Diffraction, Collimators, Filters, WDXRF spectrometers, Detectors, Gas.  May 4-8, 2020
18 Final Exam June, 2002

LEARNING OUTCOMES

On completion of the course, students will be able to

  • Analysed different compounds by using knowledge of Mass spectrometry
  • understand the basic Principle of Xray spectroscopy
  • Develop the skills in students to understand  X-ray Diffraction (XRD) process 

Analytical Chemistry Lab. (Cr.01)

  1. Verification of deviations from Beer-Lambert’s law.
  2. Determination of chloride content in drinking water samples bymercury(II) thiocyanate  spectrophotometric method.
  3. Determination of copper in various food samples by diethyldithiocarbamate spectrophotometric method.
  4. Determination of aspirin in pharmaceutical preparation and caffeine in tea               and coffee by U.V Visible Spectrophotometry involving extraction.
  5. Analysis of analgesic by HPLC.
  6. Quantitative and qualitative analysis of different fruit juices for vitamin C by HPLC.
  7. Estimation of Sodium and Potassium in biological fluids by flame photometry.
  8. Determination of calcium in milk samples by flame photometry.
  9. Determination of Magnesium in tap water, food, leaves etc by AAS.
  10. Determination of manganese content in tea leaves by AAS.
  11. Determination of sulphate and phosphate in commercial samples by complexometric titrations using EDTA.
  12. Determination of iron in pharmaceutical samples by redox titration.
  13. Determination of Sodium bicarbonate contents in baking Soda powder by conductometric titration with HCl

Description of system of evaluation (Exam, assignments etc)

 

Mid Term Exam: 15%

Sessional:     15%    (Presentation, assignment and class participation included in sessional marks)

Practical work:       25%

:  included in sessional marks

Final exam: 45%

RULES AND REGULATIONS

  1. Minimum attendance 75% is necessary to appear in exam.
  2. For practical exam also 75% attendance in practical is necessary.
  3. Keep your mobiles of/silent during class time.

Other Courses by Dr.Yasmeen Gull