Course Title: Pharmaceutics-IV (Industrial Pharmacy)

Course Code: PHARM 408

DESCRIPTION & OBJECTIVES

This course is designed to broaden the student's outlook to know about all Processes and procedures adopted for the large scale Preparations of Pharmaceuticals in Industry and deepen their interest in everything that concerns general and specialized methods of preparation of Medicines in Pharmaceutical Industry. In this course, the students will also be exposed briefly to certain specific areas of tablets, capsules, aerosols, suppositories, ointments, Syrups. The lab of this course aims to provide student’s hands-on experience to Various Industrial equipment’s to enhance their skills.

This course is an instrument of satisfying the student's handling and ability to prepare various formulations.  After studying this course, students will be able to understand the pharmaceutical drug products, excipients and methods used to formulate in Pharmaceutical Industry.

INTENDED LEARNING OUTCOMES

1. To develop interest of students towards industrial processes used for the production of Pharmaceuticals
2. To provide an update on upcoming industrial improvements
3. To inculcate various techniques used in Pharmaceutical industry
4. To provide better insight to the students for equipment’s used in industry

COURSE CONTENTS

1. EMULSIONS: Mechanical Equipments, Specific formulation consideration and Emulsion stability.

2. SUSPENSIONS: Formulation of suspensions, Equipment used in preparation and test methods for pharmaceutical suspensions.

3. SEMISOLIDS: Equipment used for Ointments, Pastes, Gels and Jellies. Packaging of ointments.

4. STERILE PRODUCTS: Sterile area and its Classification, Ophthalmic ointments, Preparation of parenterals (Building, Equipment), Complete Sterility (Aseptic area), air control, (Laminar flow etc.), air locks, Environmental monitoring methods, Sterilization, Filling/Packaging (Plastic and glass containers), Added substances (Preservatives, anti-oxidants, solubilizer, suspending agents, buffers, stabilizers etc.), Inprocess Quality Control of Parenterals (Sterility, leakage, pyrogens, clarity etc.).

5. PACKING & PACKAGING: Influence of Packaging materials, Stability, Packaging Lines, Packaging Area, Packaging Equipment.

6. SAFETY METHODS IN PHARMACEUTICAL INDUSTRY: (a) Mechanical, chemical and fire hazards problems. (b) Inflammable gases and dusts

Recommended Books

1. The Theory and Practice of Industrial Pharmacy by Lachman

2. Tutorial Pharmacy by S.J. Carter.