Week 10: purification of biopharmaceutical
Chapter 6: Downstream processing. Page 140 to 158
In this week studied about the various chromatographic techniques for the purification of biopharmaceutical or for the removal of protein based and non-protein based contaminants. In this week, we majorly discussed the ion exchange chromatography, affinity chromatorgraphy, hydrophobic interaction chromatography, gel filtration chromatography. Other than this some other types of chromatography were also studied but in less details as they were the modifications of previously studied chromatography techniques.
Course Material
- Week 1: Introduction to Pharmaceutical Biotechnology
- Week 2: Drug development process and properties of effective drug
- Week 3: impact of genomics and other technologies upon drug discovery
- Week 4: Functional Genomics, Pharmacogenomics, routes of drug administration
- Week 5: Lab scale studies, pre clinical studies and drug toxicity
- Week 6: clinical trails, role of regulatory authorities, legal and regulatory issues
- Week 7: Sources of recombinant proteins (drugs)
- Week 8: Upstream processing for production of biopharmaceutical
- Week 9: Recovering the recombinant protein at manufacturing scale
- Week 10: purification of biopharmaceutical
- Week 11: Final product formulations and its processing
- Week 12: Final product analysis: Protein based contaiminants
- Week 13: Final product analysis: Non protein based contaiminants
- Week 14: Analysis of Biopharmaceutical and validation studies
- Week 15: Polymers used in pharmaceutical industory and controlled drug release systems
- Chapters 15
- Department Biotechnology
- Teacher
Mrs. Misbah Hussain
