Configurational isomerism, relative (D/L convention) and absolute configuration (CIP rule &R/S, r/s, aR/aS conventions).
Course Material
- IUPAC nomenclature of aliphatic, alicyclic organic compounds.
- IUPAC nomenclature of aromatic and different functional group containing compounds.
- IUPAC nomenclature of multicyclic organic compounds, spiro, bridged and fused ring compounds.
- IUPAC nomenclature of polyfunctional aliphatic, heterocyclic organic compounds.
- Definitions of acid and base, Strength of acids.
- The origin of acidity in organic compounds.
- Inductive effect, resonance, hyperconjugation, aromaticity & tautomerism
- Acidity of some organic compounds, Some aliphatic acids, Substituted aliphatic acids
- Acidity of Phenols, Aromatic carboxylic acids, Dicarboxylic acids,
- Strength of Bases, Acidity of Aliphatic bases.
- Aromatic Bases, Heterocyclic bases,
- Geometrical Isomerism: cis/trans, E/Z &syn/anti conventions.
- Chirality and symmetry, elements of chirality and elements of symmetry.
- Wedge-head, saw-horse, Newman & Fischer projections. Baeyer’s Strain theory.
- Conformational isomerism in acyclic, alicyclic compounds (cyclobutane, cyclopentane, cyclohexane), mono / di-substituted cyclohexanes and condensed rings, locking groups.
- Configurational isomerism, relative (D/L convention) and absolute configuration (CIP rule &R/S, r/s, aR/aS conventions).
- Configurational isomerism in biphenyls, allenes and spiro compounds.
- Racemization, resolution of racemic modification and introductory asymmetric synthesis.
- Stereospecificity vs stereoselectivity. Determination of configuration (ORD/CD).
- Optical Isomerism
- Chapters 20
- Department Chemistry(SCB)
- Teacher
Dr. Rizwan Nasir Paracha
