Week 13-14, Eliminations reactions and 1,3-Dicarbonyl systems
Classification of elimination reactions, syn / anti eliminations, E1 vs E2 eliminations
Dependence of elimination on eliminating groups. Factors affecting eliminations
1,3-Dicarbonyl systems (diethyl malonate, acetylacetonate etc.) and their pKa. Stobbes condensation
Course Material
- Week 1-2 (Introduction and classification of the reaction mechanism)
- Week 3-4_Addition reactions involving >C=C< and ‒C≡C‒ (syn & anti)
- Week 5-6_ Aldol reactions & factors affecting addition reactions ,Electrophilic and nucleophilic substitution reactions at aromatic sytems
- Week 7-8 and 9_ Nucleophilic substitution reactions , Selectivity (regio- / chemo- / stereoselectivity) vs stereospecificity
- Week 11-12_Electrophilic substitution reactions at aliphatic C; the concept of enolization. Reformatsky, Mannich, Claisen, Claisen–Schmidt, Knovenagel, Perkin reactions
- Week 13-14, Eliminations reactions and 1,3-Dicarbonyl systems
- Week 15-16, Pylides. Wittig reaction
- Chapters 7
- Department Chemistry
- Teacher
Dr. Akbar Ali
