Week 1-2 (Introduction and classification of the reaction mechanism)
Introduction and classification of the reaction mechanism, benefits of thermodynamic and kinetic data towards reaction mechanism elucidation,
Kinetic vs thermodynamic conditions, isotopic labeling, trapping of intermediates and selectivity (regio- / chemo- / stereoselectivity) vs stereospecificity
Course Material
- Week 1-2 (Introduction and classification of the reaction mechanism)
- Week 3-4_Addition reactions involving >C=C< and ‒C≡C‒ (syn & anti)
- Week 5-6_ Aldol reactions & factors affecting addition reactions ,Electrophilic and nucleophilic substitution reactions at aromatic sytems
- Week 7-8 and 9_ Nucleophilic substitution reactions , Selectivity (regio- / chemo- / stereoselectivity) vs stereospecificity
- Week 11-12_Electrophilic substitution reactions at aliphatic C; the concept of enolization. Reformatsky, Mannich, Claisen, Claisen–Schmidt, Knovenagel, Perkin reactions
- Week 13-14, Eliminations reactions and 1,3-Dicarbonyl systems
- Week 15-16, Pylides. Wittig reaction
- Chapters 7
- Department Chemistry
- Teacher
Dr. Akbar Ali
