Course Material
- Week 1: Recombinant DNA: Recombinant DNA Technology Introduction, Basic Techniques, PCR and Rt PCR
- Week 2: Restriction enzymes, Plasmids, Bacteriophages as tools, the formation of recombinant DNA
- Week 3: Recombinant DNA methodology, Site directed Mutagenesis, DNA sequencing
- Week 4: Applications of recombinant DNA technology using prokaryotes, recombinant DNA technology in eukaryotes
- Week 5: An overview, transgenic yeast, transgenic plants, transgenic animals
- Week 6: Screening for genetic diseases, identifying disease genes, DNA typing, gene therapy, genetically modified organisms and apprehensions
- Week 7: Mechanisms of Genetic Change I: Gene Mutation: The molecular basis of gene mutations, spontaneous mutations, induced mutations, reversion analysis
- Week 8: Mutagens and carcinogens, Biological repair mechanisms
- Week 9: MID TERM EXAMINATION
- Week 10: Recombination: General homologous recombination, the holiday model, enzymatic mechanism of recombination
- Week 11: Site-specific recombination, recombination and chromosomal rearrangements
- Week 12: Transposable Genetic Elements: Insertion sequences, transposons, rearrangements mediated by transposable elements
- Week 13: Review of transposable elements in prokaryotes, controlling elements in maize
- Week 14: Human Genome Project: Strategies and application, achievement and future prospects
- Week 15: Plant Genome Projects: Arabidopsis, achievement and future prospects. Other plant genome projects
- Week 16: Bioinformatics: Application of computational tests to the analysis of genome and their gene products
- Week 17: Bioethics: Moral, Religious and ethical concerns
- Week 18: FINAL TERM EXAMINATION
- Chapters 18
- Department Botany
- Teacher