Course Title: Physiology of Endocrine Coordination 
Course Code: ZOL-745
Credit Hours: 04
Instructor: Dr. Khawaja Raees Ahmad

Introduction to course

Endocrinology is the most interesting field of animal and human physiology with multiple applications. Where typically Hormones and their physiological applications are studied. In present course of study  hormones various human and animal endocrine glands their biochemistry, regulation of secretory mechanisms, and the physiological, developmental as-well-as  behavioral applications will be studied.    

Course pre requisites (if any)

Basic human physiology and physiological mechanisms should be known to the students 

Learning outcomes

1. This course will inculcate the concept, need and importance of coordination in the students 

2. It will develop a discrete concept of types, components and mechanisms of endocrine coordination, its similarities, departures and integration to that of the Nervous coordination. 

3. The students will have a comprehensive understanding of the endocrine glands, hormones, evolution of hormonal applications, hormonal interplay (synergism, antagonism) and feedback control mechanisms. 

4. It will also decipher basic knowledge of Biochemistry, synthesis, release and transport of hormones and their mechanisms to illicit specific responses in the target organs 

Textbooks to be used for the course

1. Randall, D., Burggren, W., French, K. and Fernald, R., 2002. Eckert Animal Physiology: Mechanisms and Adaptations, 5th Ed. W.H. Freeman and Company, New York

2. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc.

3. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education

4. Fox SI. Human physiology. 2016. 14th ed. McGraw-Hill Education, 2 Penn Plaza, New York, NY 10121.

Description of system of Evaluation (Exam, assignments etc.)

Term paper in lieu of Mid-term :30

Final term :50

Sessional :20 (Class Participation)

Time Table w.e.f. Jan13, 2020: M. Phil Zoology 2nd semester Wednesday: 9-10AM; Thrusday: 09-10 and 10-11AM 

Detailed lesson plans for each lecture/week

Week 1: General principles of endocrine physiology

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp: 124-145
2. Fox SI. Human physiology. 2016. 14th ed. McGraw-Hill Education, 2 Penn Plaza, New York, NY 10121.pp 153-156

Week 2: Hormones in homeostasis of metabolism

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp: 9-16
2. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education. Pp7-14

 Week 3: Endocrine regulation of metabolism of calcium and phosphate, Parathyroid gland, Calcitonin and Cholecalciferol

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp 549-555
2. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education. Pp352-356

Week 4: Hypothalamus and Pituitary: Hypothalamic regulation of pituitary

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp149-154
2. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education. Pp333-339

Week 5: Pituitary gland hormone in physiological coordination

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp 149-154
2. Fox SI. Human physiology. 2016. 14th ed. McGraw-Hill Education, 2 Penn Plaza, New York, NY 10121.pp331-337

Week 6: Thyroid gland: Functional anatomy, biosynthesis, regulation and roles in physiological functions, mechanism of thyroid hormones action

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp154
2. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education. Pp339-343

Week 7: Adrenal cortex: Hormones biosynthesis, physiological roles and control, Hypothalamic-pituitary-adrenocortical axis

Suggested Book reading:

1.  Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp154-155
2. Widmaier, EP., Vander, AJ. 2019. Vander’s human physiology: the mechanisms of body function. New York, NY : McGraw-Hill Education. Pp344-348

Week 8: Adrenal medulla: Hormones biosynthesis, physiological roles; adrenal medulla and sympathetic nervous system together integrate responses to stress

Suggested Book reading:

1.  Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp155
2. Fox SI. Human physiology. 2016. 14th ed. McGraw-Hill Education, 2 Penn Plaza, New York, NY 10121.pp 337-340

 Week 9: Endocrine function of kidney, heart and pineal gland;

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp154, 532-555
2. Fox SI. Human physiology. 2016. 14th ed. McGraw-Hill Education, 2 Penn Plaza, New York, NY 10121.pp 346-348

Week 10: General reproductive mechanisms: Energetics of reproduction;

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp631-638

Week 11: Functional anatomy, synthesis and regulation of gonadal steroids, secretary pattern of gonadal steroid at different stage of life

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp638-640

Week 12: Male reproduction: Roles of androgen, biology and regulation of spermatogenesis, male puberty

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp640-645

Week 13: Female reproduction: Roles of ovarian steroids

Suggested Book reading:

1.  Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp645-655

Week 14: Biology and regulation of oogenesis

Suggested Book reading:

1.Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp645-655

Week 15: Female puberty, cyclic changes and adaptations in gestation

Suggested Book reading:

1. Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp655-651

Week 16: Parturition, lactation and menopause

Suggested Book reading:

1.  Cindy L. Stanfield. 2013. Principles of human physiology -5th ed. Pearson Education, Inc. pp661-664