This course is developed to develop basic concepts and logical understanding about Organometallic and bioinorganic chemistry

Course contents

Nature of metal-carbon bonds: Compounds with Metal-Carbon single bonds; Compounds with Metal-Carbon π- bonds; Classification of organometallic compounds and 18- electron rule.

Compounds of transition metals: Single, double and triple bonds to carbon, (compound types, Acyls, Alkylidene complexes and alkylidyne complexes), delocalized hydrocarbon systems, (alkene, olefins, allyl and Butadienes), Alkyne complexes, Cyclic π complexes (four, five and six member rings),

Fundamental Process in Reactions of Organotransition Metal Complexes: Ligand Coordination & dissociation; Oxidative addition & reductive Eliminations; Insertion & Extrusion reactions; Reaction of Coordinated ligands, Applications of organometalic compounds in synthetic chemistry and industry.

Bio-Inorganic chemistry: Essential elements, Biochemistry of iron (iron storage and transport), Haemoglobin and myoglobins, Cytochromes, other natural oxygen carrier, Biochemistry of other metals (Zn, Cu, Co, Cr, Ni, and V), Metal based drugs.

Readings

1. Akio Yamamoto, Organometallic Chemistry, Wiley, New York.

2. Robert H. Crabtree, The organometallic chemistry of transition metal, Wiley, New York

ASSESSMENT CRITERIA

Mid Term: 30%

Sessional: 20%

Presentation: included in sessional marks

Final exam: 50%

Course Schedule