• Overview of Protein Structures;
• Secondary, Tertiary, and Quaternary structures,
• Classification of proteins according to their functions,
• Protein families on basis of structure;
• Secondary and Tertiary Structure prediction,
• X-ray crystallography and NMR spectroscopy of proteins,
• Molecular modeling and other techniques are used to solve structures and develop models of macromolecules;
• Genomes and Proteins;
• Protein folding pathways;
• Protein denaturation;
• Protein Engineering;
• Production of Recombinant Proteins;
• Post-translational and Post-transcriptional modifications;
• Chemical modification and site-directed mutagenesis;
• Gene shuffling and chimeric enzymes; 
• In vitro directed evolution of enzymes and other proteins.

Evaluation

1. Assignments
2. Presentations
   1. Assignment Presentations
   2. Poster (from a selected research paper)
3. Quizzes (Weekly quizzes, including surprise tests)

Recommended Books

1. Bujnicki, J. 2009. Prediction of Protein Structures, Functions, and Interactions. John Wiley & Sons, New York.

2. Creighton, T.E. 2005. Proteins: Structures and Molecular Properties. John Wiley & Sons, New York.

3. Whitford, D. 2005. Proteins: Structure and Function. John Wiley & Sons, New York.

4. Branden, C and Tooze, J. 1999. Introduction to Protein Structure. 2nd Edition. Garland Science.

5. Voet, D. Voet J.G and Pratt, C.W. 1999. Fundamentals of Biochemistry. John Wiley & Sons, New York.

6. Stryer, L. 2002. Biochemistry. 5th Edition. W.H. Freeman & Co.

7. Lesk, A.M. 2003. Introduction to protein Science. Oxford Publishers.