UNIVERSITY OF SARGODHA

DEPARTMENT OF CHEMISTRY

Course Outline (Forensic Chemistry)

SEMESTER:

CLASS:

LECTURES ON:

Fall Semester 2020

M.Sc. III (R)

Thursday and Friday at 11.15 – 12.15 am

Course Title

Forensic Chemistry

Course Code

CHEM-601

Course Website

www.uosbiochemistry.com

Credit Hours

2 cr hr,     Lecturers per week : 02      Duration: 1.0 Hrs

Prerequisite

General Biochemistry Course

Course Teacher:

Contact:

E-Mail:

Dr. M. Fayyaz ur Rehman

0300-4474407

[email protected]

Follow Up

Environmental Chemistry

Category

Chemistry (Compulsory Subject)

Aims and Objective

The course introduces students to a study of the basic Principles of Forensic sciences. This course aims at introducing to students about:

  • Types of evidences used for forensic analysis.
  • How the different sciences relate to forensics sciences.
  • How the forensic evidences are analyzed by physical and chemical methods.
  • Processing and storing of different evidences
  • Chemical analysis of toxic compounds and drugs.
  • DNA forensics, involving latest DNA typing and DNA fingerprinting techniques. 

Learning Outcome

This subject will integrate the concept and techniques developed in chemistry, physiology and biochemistry and apply them to the pharmacology and detection of drugs and toxins. Students will be expected to gain an understanding of the collection, storage, analysis and interpretation of physical and trace forensics evidences. Upon completion of this course students will be able to describe various biochemical and chemical tests for forensic samples. Where students will be able to understand lab forensic sample analysis i.e. hair, fiber, fingerprint analysis, they are also expected to grasp advanced molecular level forensic approaches i.e. DNA fingerprinting typing and high throughput sample analysis. At the end of course students will be able to understand drug/toxin analysis and their mechanism of action as well as their antidotes.

Syllabus

Important topics in forensic science i.e. History of forensic sciences fingerprinting, forensic serology, hair and fiber analysis, explosive residues, glass comparisons, drug analysis, bullet and cartridge analysis, DNA analysis, Forensic botany and forensic toxicology.

Reading List/Text Books

  1. Bell, Suzanne, Forensic Chemistry, 1st Edition, 2006, Prentice Hall,
  2. Jackson, Andrew R. W. and Julie M. Jackson, Forensic Science, 2004 1st Edition Prentice Hall
  3. Khan, Javed, Kennedy, Thomas J., Christian, Jr., Donnell, Basic Principles of Forensic Chemistry2009, Human Press
  4. W.G. Eckert, Introduction to Forensic Sciences, Second Edition, Elsevier, New York, 1992.
  5. N.E. Genge, The Science of Crime Scene Investigation: The Forensic Casebook, Ballentine Books, New York 2002.

Reference Material

  1. D. P. Lyle, MD, Forensics for Dummies, John Wiley & Sons, 2004
  2. Anthony J. Bertino, Forensic Science: Fundamentals and Investigations 2012 Update, Cengage Learning, 2012
  3. D. Voet, J. G. Voet, and C. Pratt, Fundamentals of Biochemistry: Life at the Molecular Level, 3rd Edition, John Wiley and Co (2008).
  4. Lehninger, A. L. Principles of Biochemistry, 4th Ed. Worth Publisher, New York (2001).Stryer, L. “Biochemistry”, Freeman & Co. ( Robert, Harper’s Biochemistry, 25th Edition. (2000).

Instructional Aids

Handouts, Notes, Computer Animations, Practical Illustration and models.

Assessment Criteria

Sessional (20)

Midterm (30)

Final (50)

Total

Quizzes/Tests

3

Objective

10

Objective

15

100

Assignments

8

Subjective

20

Subjective

35

Presentations/

Attendance

7

 

 

 

 

Class Participation

2

Recommendations

Consult reference rooks as well as internet for the preparation of assignments and quizzes.  

 

 

WEEKLY LECTURE SCHEDULE

Thirty two Lectures (Duration: 1 hr)

 

For semester starting from 3rd September, 2018

 

Week

Lecture

Topic

Source (Book)

Recommendations/Learning Activities

1

1

History of Forensic science/forensic chemistry, Applications of forensic sciences

Book # 2

Handouts/Notes

2

Relationship of forensic sciences with other sciences e.g. Botany, Zoology, Chemistry, Geology, Odontology, Pathology etc

Book #  1, 2

Handouts/Notes

2

3

Types of evidence, Physical, chemical biological evidence, Classifications of forensic evidences

Book # 3

Handouts

4

Physical evidences, processing, collection, storage, trace evidences, Direct and indirect evidences

Book # 1, 2, 3

Class Assignment

3

5

Hair as a forensic physical evidence, composition and structure of hair, differences between human and animal hair

Book # 2, 3

Handouts/Notes

6

Fiber as a forensic evidence, composition, chemical composition, microscopic analysis, chemical tests

Book # 2, 3, 4

Class quiz

4

7

Glass as a forensic evidence, Physical and chemical properties of glass, chemical analysis

Book # 1,3,

Presentations

8

Trace evidences, Physical and chemical properties, qualitative and quantitative metal analysis, Microscopic analysis

Book # 3, 4

Presentations

5

9

Trace evidence types, characterization, chemical tests, collection, analysis, exhibiting in court, paints, vehicles, fire

Book # 2, 3

Presentations

10

Trace evidence, forensic geology, soil analysis, Physical and chemical properties, comparison, Minerals, sand and rock analysis Glass and soil evidence collection, processing, analysis

Book # 2, 3

Presentations

6

11

Fingerprint analysis, history, types, latent vs visible fingerprints

Book # 3

Class quiz

12

AFIS, fingerprint database, chemical tests for fingerprints

Book # 2, 3

Class Assignment

7

13

Footprint as forensic evidence, Foot print casting, storage and analysis, tyre prints, teeth print analysis

Book # 2, 3

Presentations

14

Toxicology, History, relation with other sciences, introduction to drugs, narcotics, toxins, laws related to poisons

Book # 2, 5, 6

Visual Animation

8

15

Classification of poisons, organic, inorganic and mechanical poisons

Book # 1, 2

Midterm Exam

16

Corrosives, irritants, neurotics, and miscellaneous poisons

Book # 2, 7, 8

Midterm Exam

9

17

Mechanisms of poisons, methods of administration, routes of excretions

Book # 1, 3

Visual Animation

18

Diagnosis of poisons, General and specific poison treatment

Book # 2, 3, 7

Presentations

10

19

Poison antidotes, Prognosis and diagnosis. Chemical tests

Book # 2, 3, 7

Class quiz

20

Analytical chemistry techniques for drug and poison analysis

Book # 2, 3, 7

Class Assignment

11

21

Separation techniques, Elemental analysis, thermal analysis,

Book # 2, 3, 7

Class quiz

22

Body fluids as forensic evidence, Blood and semen analysis

Book # 2, 3, 7

Presentations

12

23

Blood pattern analysis, Chemical tests for poison detection

Book # 2, 3, 7

Class Assignment

24

Death analysis, Algor mortis, Livor mortis, Rigor Mortis, lividity and Postmortem changes in body

Book # 2, 3, 7

Presentations

13

25

Accidental death and murder forensic analysis, chemical tests to determine mode of death

Book # 2, 3, 8

Visual Animation

26

Forensic botany and entomology, and forensic odontology

Book # 2, 3, 8

Class quiz

14

27

Explosives, bullets, cartridge analysis and comparisons, chemical tests for gunpowder

Book # 2, 3, 8

Presentations

28

Forensic biology, PCR DNA amplification, sources of DNA, and RNA and their isolation

Book # 3,7, 8

Visual Animation

15

29

DNA databases, CODIS databases, Forensic DNA markers

Book # 3, 8

Presentations

30

DNA typing, RFLP, SNP, VNTR, Mitochondrial DNA analysis

Book # 3, 8

Presentations

16

31

DNA Fingerprinting, paternity tests

Book # 2, 7

Handouts/Notes

32

DNA forensic Applications, STRs, genetic markers 

 

 

 

Course Material