COURSE OUTLINE                                                                                                 FALL 2020

Course Title:    METABOLISM OF PRIMARY NUTRIENTS 

Course Code: AN-303                       

Credit Hours: 2(1-1)  

           

                       

DESCRIPTION & OBJECTIVES

After taking this course students will be able to understand biochemical basis of primary nutrients

READINGS

1. Sarwar, M. and Zia-ul-Hasan. 2000. Nutrient Metabolism in Ruminants. University of Agriculture Press, Faisalabad.

2. Maynard, L.A. J.K. Loosli, H.F. Hintz and R.G. Warner. 1991. Animal Nutrition. 7thEd.McGraw Hill Book Co. Inc., New York, USA.

3.  McDonald, P., R. A. Edwards and J. F. D. Greenhalgh. 1996. Animal Nutrition. Longman Scientific and Technical Publisher, U.K.

4.  Pond, W. G., D.C. Church and K. R. Pond. 1995. Basic Animal Nutrition and Feeding. 4th Ed. John Willey and Sons, New York, USA.

5.  Moren, L. A. 1994. Biochemistry. Neil Peterson Publishers, Prentice Hall Inc., USA.

CONTENTS

Theory:Metabolic functions of water. Metabolism of carbohydrates:  classification, digestion, absorption and utilization in monogastric and ruminant animals; glycolysis, lactic acid and  volatile fatty acid fermentation, citric acid cycle, pentose phosphate pathway, gluconeogenesis, glycogenesis and glycogenolysis. Metabolism of Lipids: classification, digestion, absorption and utilization in monogastric and ruminant animals; beta oxidation of fatty acids, fate of glycerol with respect of fat synthesis, glucose/glycogen synthesis and its oxidation, storage of fat, catabolism of fat and ketosis. Metabolism of proteins: classification,  digestion, absorption and utilization in monogastric and ruminant animals; essential and non-essential amino acids, protein quality, fate of absorbed amino acids, transamination, deamination, deamidation, transmethylation, decarboxylation and interconversion of amino acids;. utilization of non-protein nitrogenous compounds in ruminants.

Practicals:Proximate analysis of feeds and feed ingredients: determination of dry matter, crude protein, ether extract, crude fiber and total ash. Acid detergent fiber (ADF) and neutral detergent fiber (NDF) analysis.

 

 

 

COURSE SCHEDULE

Week

Topics and Readings:

Dates

1

Metabolic functions of water

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-18)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients

14/10/20

2

Metabolism of carbohydrates:  classification, digestion, absorption and utilization in monogastric and ruminant animals

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients

21/10/20

3

Glycolysis

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  crude protein

28/10/20

4

Lactic acid and  volatile fatty acid fermentation

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  crude protein

04/11/20

5

Citric acid cycle

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  ether extract

11/11/20

6

Pentose phosphate pathway

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  ether extract

18/11/20

7

Gluconeogenesis, glycogenesis and glycogenolysis.

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  ether extract

25/11/20

8

Metabolism of Lipids: classification, digestion, absorption and utilization in monogastric and ruminant animals

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  ether extract

02/12/20

9

Beta oxidation of fatty acids

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  Crude Fiber

16/12/20

10

Fate of glycerol with respect of fat synthesis, glucose/glycogen synthesis and its oxidation, storage of fat, catabolism of fat and ketosis

Animal Nutrition (7th edition) by McDonald (page 227-312)

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  Crude Fiber

23/12/20

11

Metabolism of proteins: classification,  digestion, absorption and utilization in monogastric and ruminant animals

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  Total Ash

13/01/21

12

Essential and non-essential amino acids, protein quality

Nutrient Metabolism in Ruminant by Sarwar (Page 1-201)

Practical: Proximate analysis of feeds and feed ingredients: Determination of  Total Ash

20/01/21

13

Fate of absorbed amino acids, transamination, deamination, deamidation, transmethylation, decarboxylation and interconversion of amino acids

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Practical: Determination of  Acid detergent fiber (ADF) analysis.

27/01/21

14

Fate of absorbed amino acids, transamination, deamination, deamidation, transmethylation, decarboxylation and interconversion of amino acids

The Ruminant animal digestive physiology and Nutrition by D.C Church (108-116,217-226, 227-312, 401-420)

Practical: Determination of  Acid detergent fiber (ADF) analysis.

03/02/21

15

Utilization of non-protein nitrogenous compounds in ruminants

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Determination of neutral detergent fiber (NDF) analysis.

10/02/21

16

Utilization of non-protein nitrogenous compounds in ruminants

Animal Nutrition 6th edition by Leonard A. Maynard and Loosli (page 67-153)

Practical: Determination of neutral detergent fiber (NDF) analysis.

10/02/21

 

ASSIGNMENT CRITERIA

Write here the distribution of marks. You can chose any or all from the below for the purpose

Sessional: 2

Presentation: 1

Participation: 1

Mid-term: 06

Final Exam: 10

Practical Exam: 20

RULES AND REGULATIONS

Following items are mandatory:

  • 80% class attendance.
  • Maintenance of Practical Copy.
  • Participation in all practical performances or class activities.

Course Material