COURSE OUTLINE                                                                                     SPRING 2020

Credit Hours:   4 (3 +1)

Instructor:        Dr Waseeq Ahmad Siddiqui

Email:             [email protected]

• Introduction:

The students of BS (Chemistry) are taught this course during 8th semester. This course defines "Catalysis", explains its types and the application of metals in catalysis. The student being introduced with honomogeneous and heterogeneous catalysis learns about role of various metals in catalysis. The pivotal point is the switch over of transition metal between at least any two oxidation states. It includes: 

i) useful application of the useless exhaust gas mixture named "Syngas" for the processes like: Hydroformylation, Reductive carbonylation and reduction of CO by hydrogen

ii) The carbonylation reactions include: water gas shift reaction, synthesis of methanol and methyl acetate, Adipic ester, other Carbonylation reactions and some decarbonylation reactions

iii) The Catalytic addition of molecules to C – C multiple bonds includes the examples of homogeneous hydrogenation, Hydrocylation and Hydrocynation.

• Learning Outcomes:

i) This course is designed to make students of BS-VIII level capable of understanding the dynamics and phenomena of homogeneous catalysis of transition metal complexes.

ii) It will help students practically for further higher studies, especially in production of organic compounds by synthetic means

iii) The students will be able to understand reactions and mechanisms involved in catalysis.

iv) The contribution of each metal, its salt in particular oxidation state will be understood by the student and he will be able to substitute the analogous metal salts for similar catalysis.

v) The students will be able to economize reactions on industrial level.

• Literature text/reference/ recommended Books:

1. Reaction Mechanisms of Inorganic and Organometallic Systems, Jordan, R. B., 2nd Edition, Oxford University Press, (1998).
2. Chemistry and Chemical Reactivity, Kotz, J. C. and P. Treichel, 4th Edition, Saunders College Publishing, (1999).
3. Synthesis and Technique in Inorganic Chemistry, Angelici, R. J., Ist Edition, University Science Books, (1986).
4. Inorganic Chemistry, Garry L. Miessler, Donald A. Tarr, 3rd Edition, Pearson Education, Inc. (2004).
5. An Introduction to Inorganic Chemistry, Keith F. Purcell and John C. Kotz, Saunder College, Philadelphia (1980).

• Contents: 

Homogeneous Catalysis by Transition metal complexes

 i) Reaction of CO and Hydrogen (Hydroformylation, Reductive Carbonylation, Reduction of CO by hydrogen, Synthesis gas and the water gas shift reaction)

ii) Carbonylation reaction (Synthesis of methanol and methyl acetate, Adipic ester, other Carbonylation reactions, Decarbonylation reactions)

iii) Catalytic addition of molecules to C – C multiple bonds (Homogeneous hydrogenation, Hydrocylation and Hydrocynation) Instrumental Methods of Analysis

Lab. work:

a) Conductometry  

1. Titration of Strong acid and Weak acid with a Strong base
2. Precipitation Titration involving AgNO3 and KCl
3. Determination of Dissociation Constant (Ka) for Acetic Acid

 b) Spectrophotometry (Colorimetry)

• Detailed Lesson Plans for each Lecture/week; 

• Week	Topics and Readings	Dates
  1.	Introduction of Homogeneous Catalysis by Tr. metal complexes	Week 01
  2.	Reaction of CO and Hydrogen,  Hydroformylation	Week 02
  3.	Reductive Carbonylation	Week 03
  4.	Reduction of CO by hydrogen	Week 04
  5.	Synthesis gas and the water gas shift reaction	Week 05
  6.	Carbonylation reaction	Week 06
  7.	Synthesis of methanol	Week 07
  8.	Mid Term Examination	Week 08
  9.	Synthesis of methyl acetate	April 01-03
  10.	Synthesis of  Adipic ester	April 08-10
  11.	Other Carbonylation reactions	April 15-17
  12.	Decarbonylation reactions	April 22-24
  13.	Catalytic addition of molecules to C – C double bonds	April 29-30, May 1st
  14.	Catalytic addition of molecules to C – C triple bonds	May 06-08
  15.	Homogeneous hydrogenation	May 13-15
  16.	Hydrocylation and Hydrocynation	May 20-22
  17.	Final-Term Examination	May 27-29