Week:11-1: Isotopic labeling and trapping of intermediates
Course Material
- Week:1-1: Enolization
- Week:1-2: Base catalyzed aldol condensations
- Week:2-1: Acid catalyzed aldol condensations
- Week:2-2: Cross Aldol & Aldol dehydration
- Week:2-3: Aldol cyclization
- Week:3-1: Cannizzaro Reaction
- Week:3-2: Claisen reaction
- Week:4-1 & 2: Cross Claisen and Dieckman condensation
- Week:5-1: Knovenagel reaction
- Week:5-2: Perkin reaction
- Week:6-1 & 2: Reformatsky and Blaise reaction
- Week:7-1: Stobbes Condensation
- Week:7-2: Darzen’s glycidic ester synthesis
- Week:8-1: Mannich reaction
- Week:8-2: Wittig reaction
- Week:9: Mid Term Examination
- Week:10-1: Introduction and classification of reaction mechanism on different basis
- Week:10-2: Introduction and classification of reaction mechanism on different basis-II
- Week:10-3: Benefits of thermodynamic and kinetic data towards reaction mechanism. Kinetic vs thermodynamic control
- Week:11-1: Isotopic labeling and trapping of intermediates
- Week:11-2: Selectivity (Regio-, Chemo- and Stereoselectivity) vs Stereospecificity
- Week:12-1: Syn vs anti additions.Reduction of alkene by reducing agents
- Week:12-2: α-Elimination reaction and kinetics investigation
- Week:13-1: β-Elimination reaction and kinetics investigation
- Week:13-2: E1cB eliminations
- Week:14-1 & 2: SN1 and SN2 reaction mechanism
- Week:15-1: SNi mechanism
- Week:15-2: Neighboring group participation, SN1' and SN2'
- Week:16-1: Syn and anti-oxidation of Alkene; alkene hydroxylation and epoxidation
- Week:16-2: Ozonolysis of alkene; cleavage of alkene to carbonyl compounds
- Week:17-1: Reduction of alkene
- Week:17-2: Conjugate (1,4-) vs direct (1,2-) additions
- Week:18: Final Examination
- Chapters 33
- Department Chemistry(SCB)
- Teacher
Dr. Muhammad Saleem
