Week:16-1: Stobbes Condensation
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Course Material
- Week: 1-1: Introduction and classification of reaction mechanism on different basis-II
- Week: 1-2: Introduction and classification of reaction mechanism on different basis
- Week:1-3: Benefits of thermodynamic and kinetic data towards reaction mechanism. Kinetic vs thermodynamic control.
- Week:2-1: Isotopic labeling and trapping of intermediates.
- Week:2-2: Selectivity (Regio-, Chemo- and Stereoselectivity) vs Stereospecificity
- Week:3-1: Syn vs anti additions.Reduction of alkene by reducing agents
- Week:3-2:α-Elimination reaction and kinetics investigation
- Week:4-1: β-Elimination reaction and kinetics investigation
- Week:4-2: E1cB eliminations
- Week:5-1-2:SN1 and SN2 mechanism
- Week:6-1:SNi mechanism
- Week:6-2:Neighboring group participation, SN1' and SN2'
- Week:7-1:Syn and anti-oxidation of Alkene; alkene hydroxylation and epoxidation
- Week:7-2:Ozonolysis of alkene; cleavage of alkene to carbonyl compounds
- Week:8-1:Reduction of alkene
- Week:8-2: Conjugate (1,4-) vs direct (1,2-) additions
- Week:9: Mid Term Examination
- Week:10-1: Enolization
- Week:10-2: Base catalyzed aldol condensations
- Week:11-1:Acid catalyzed aldol condensations; aldol dehydration; aldol cyclization
- Week:11-2:Cross aldol
- Week:11-3: Aldol cylization
- Week:12-1: Cannizzaro Reaction
- Week:12-2:Claisen reaction
- Week:13-1 & 2:Cross Claisen and Dieckman condensation
- Week:14:1: Knovenagel reaction
- Week:14-2: Perkin reaction
- Week:15: 1 & 2: Reformatsky and Blaise reaction
- Week:16-1: Stobbes Condensation
- Week:16-2: Darzen’s glycidic ester synthesis
- Week:17-1: Mannich reaction
- Week:17-2: Wittig reaction
- Week:18: Final Examination
- Chapters 33
- Department Chemistry(SCB)
- Teacher
Dr. Muhammad Saleem
