Pharmaceutical Surfactants

Surface-active agents (usually referred as surfactants, synthetic and biobased) are active at interfaces and possess both polar (hydrophilic) and non-polar (hydrophobic) characteristics in the same molecule. The hydrophobic part is referred to as the head group and the hydrophobic part as the tail. For pharmaceutical products poorly soluble in water, the use of surfactants becomes inevitable to reduce the interfacial tension between the medium and the drug and to increase solubility of drugs.