Clinical pharmacy provides a platform to perform activities through which pharmacist cooperates and coordinates with other health professionals in designing, implementing and monitoring a therapeutic care plan in order to give better care to patients evaluation and review of drug utilizationprocess. It provides understanding regarding monitoring, reporting and management of various types of adverse drug reactions with a thorough knowledge of factors affecting them. It plays a critical role in understanding of different drug interactions like drug-drug, drug-food, drug-lab and drug-disease interactions. The subject enables students to find and manage drug induced diseases and their management.  The students will also have an insight of role of computers in e-prescription, clinical trials, clinical research and data management in different clinical settings. The students will gain a competency regarding how to write and how to evaluate drug literatures.  Students will learn the practical skills of taking patient’s history, dose calculation for pediatric patients and establish drug information resources.

INTENDED LEARNING OUTCOMES

At the end of this course, students will have a better understanding of clinical pharmacy, its scope and practice. They will be able to communicate with the patients in an effective way. Moreover, they would be able to collect and analyze case studies of various patients.

CONTENTS

1. RATIONAL USE OF DRUGS: Rational Prescribing, Rational Dispensing, Problems of Irrational Drug Use, Learning about drug use problem, Sampling to study drug use, Indicators of drug use.

2. INTRODUCTION TO ESSENTIAL DRUGS: Criteria for selection, Usage and Advantages. Development of EDL.

3. DISEASE MANAGEMENT:

• Unit V: Central nervous system unit (Stroke, epilepsy, Psychosis)
• Unit VI: Infectiuos diseases ( Meningitis, tuberclosis, dermatological infections, Rabies, Urinary track infection, Malaria fever, typhoid fever, fungal infections of skin, Dengue Fever, Common Cold, Pharyngitis & Tonsillitis, Conjunctivitis)
• Unit VII: Endocrinlology Unit (Diabeties Mellitus, Hyper/Hypo thyroidism, pitutary gland non-malingnant disorders)

4. DRUG UTILZATION EVALUATION & DRUG UTILIZATION REVIEW (DUE/DUR): Development of protocol of use of few very low therapeutic index drug groups like Steroids, Vancomycin and Cimetidine.

5. CLINICAL PHARMACOKINETICS: Therapeutic Drug Monitoring of Digoxin, Theophyline, Gentamycin, Lithium, Phenytoin, Cabamazepine, Phenobarbitone, Valproic Acid, Cyclosporins and Vancomycin.

READINGS

1. DiPiro JT. Encyclopedia of Clinical Pharmacy. 1st Ed. Informa Healthcare; 2002.

2. Gennaro AR. Remington: The science and practice of pharmacy. 21st Ed. Lippincott

     Williams & Wilkins; 2011.

3. Gourley H. Clinical Pharmacy & Therapeutics. 4th Ed. William&Willkins; 1992.

4. Hansten P, Horn J. Drug interactions Analysis and Management. 5th Ed. Lippincott

    Williams & Wilkins; 2010.

5. Koda-Kimble MA, Young LY, Kradjan WA, Guglielmo BJ, Alldredge BK, Corelli RL. Applied

    therapeutics: the clinical use of drugs. Lippincott Williams & Wilkins Baltimore; 2005.

6. Poisoning and drug overdose by the faculty, staff associates of California poisoning control

      system edited by Kent R Olson Lange clinical manual

7. Sweetman S. Martindale: The complete drug reference. 37th Ed. Pharmaceutical Press.

      2011.

8. Walker R. Clinical Pharmacy & Therapeutics. 4th Ed. Churchill Levingstone; 2003.

9. Winfield AJ, Rees J, SmithI.Pharmaceutical practice. 4th Ed. Churchill Livingstone; 2009.

10. Zinc G. Comprehensive Pharmacy ReviewPhiladelphiaCollege of

      Pharmacy and Science: New York 1157; 2005

COURSE SCHEDULE

RESEARCH PROJECT

• Advanced Clinical Pharmacy Based Research Projects

ASSESSMENT CRITERIA

Sessional: 20% (Ward rounds and clinical case studies)

Mid exam: 30% 

Final exam: 50%

RULESANDREGULATIONS

Following are the rules and regulations that students have to abide by in my class

• Class attendance. (80% class attendance)
• Study of course materials as specified by the instructor
• Completion of given task on time