To acquaint the students with the fundamentals of biochemical engineering. The objective of this course is to introduce the basic concepts of biomolecule and the cell function and how they are applied to bioreactor analysis and its design. The students will also be able to develop a clear picture of what enzymes are, what their function is and the mechanistic models describing their function in biochemical reactions. Through this course, the students will grasp knowledge about the mechanisms and energetics of metabolic pathways in the cell and the various patterns and calculations involved in describing cell growth. This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism will also be covered during this course. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.

INTENDED LEARNING OUTCOMES

On successful completion of the course you should be able to:

1. Describe and identify the main groups of microorganisms 

2. Describe and compare the different structures and growth modes of diverse microorganisms 

3. Describe and explain how (microbial) genetics determines microbial metabolic and functional activity. 

4. Describe key biochemical and cellular components and biochemical pathways

5. Explain how microorganisms and biochemical processes can be applied in engineered systems and processes. 

6. Undertake a range of practical approaches associated with microbiology and biochemistry e.g. microbial isolation and culture, microscopy biochemical and genetic analyses and be able to record, describe, present and explain data

ASSESSMENT CRITERIA

Sessional: 15

Midterm exam: 15

Practical: 25

Final exam: 45

Books:

Inamdar STA. 2012. Biochemical Engineering; Principals and Concepts. 3rd edition. PHI pvt Ltd.

Katoh, S. and Yoshida, F. 2009. Biochemical Engineering: A textbook for engineers, chemists and biologists.  Wiley-VCH