UNIVERSITY OF SARGODHA

COURSE OUTLINE                                                  Semester: Spring 2020

Course Tittle: Analytical Chemistry 

Course Code: CHEM-311

Credit Hours: 3+1

Class: BS 6th (Regular, SS, EX-PPP)

Instructor: Dr. Farooq Anwar

Email: [email protected], [email protected]

DESCRIPTION & OBJECTIVES

The course mainly focuses on basics principles and methods of Analytical Chemistry and qualitative and quantitative aspects of chemical analyses. Different aspects of Analytical Chemistry (Analytical Science) including from problem defining to classification of analytical methods, sample collection, necessary preparations, measurements, data presentation and data interpretation are covered. Moreover, solution preparations, laboratory safety measurements and first aid practices, disposal of waste materials, use of glass ware, their cleaning and calibration are discussed. Lab safety measures and routine laboratory practices such as extraction, distillation, ashing, digestion etc. are also covered. In addition to learning about basics (principle, theory, historical developments, and classification) of chromatography, details about thin layer chromatography, column chromatography, ion exchange chromatography, and electrophoresis will be covered in detail along with their applications. The main objective of this course is to impart knowledge of analytical chemistry to students with a practical approach so as to enabling them to apply principles and techniques of analytical chemistry for the accomplishments of different experiments as well as qualitative and quantitative analyses.    

LEARNING OUTCOMES

The students will acquire knowledge of the basics of Analytical Chemistry, design and preparation of samples, classification of analytical methods and qualitative and quantitative analyses and statistical data analysis and will be able to practically use basic and modern analytical techniques to solve chemical problems. They will come to know about different routine laboratory practices including weighing, solution preparations, standardization, and use of glassware. Moreover, they will acquire/ gain technical knowledge about different solvent extraction and chromatographic techniques and can be able to apply these methods for the qualitative and quantitative analyses.  Practical knowledge technical know-how based approach imparted to students will enable them to work as good analytical chemists in various industrial sectors and contribute towards solving the society need based research problems with the growing perspectives of knowledge-based economy.

READINGS

1. Harris, D.C.  Quantitative Chemical Analysis, 9th edition Freeman, NY (2015).
2. Christian, G.D. Analytical Chemistry, 7th edition John Wiley & Sons, NY (2013).
3. Skoog, D. A. West, D. Holler, J. M.F., Crouch S. R. Fundamentals of Analytical Chemistry. 9th ed. Saunders College Publishing, Philadelphia. (2013).
4. Nikalje, Anna. A Handbook of Chromatography, Scholar's Press Verlag Omniscriptam, Deutschland, Germany (2017)
5. Elena Ibanez Alejandro Cifuentes, Green Extraction Techniques: Principles, Advances and Applications, 1st Edition, Elsevier, (2017); https://www.elsevier.com/books/green-extraction-techniques-principles-advances-and-applications/ibanez/978-0-12-811082-9

COURSE CONTENTS

Data Handling:  Introduction to Analytical Chemistry, Sampling; Types of samples,  Techniques/ Steps involved in sample preparation, Drying and ignition, Weighing,  Analytical balance, its construction working volumetric glassware, Errors in measurements,  Calibration of glassware, Steps involved in chemical analysis, System for units of  measurements and their inter conversion, Chemical concentration and preparation of  solutions, Calibration and calibration curves(construction and interpretation), Standard  addition and internal standard methods, Statistical treatment of analytical data; Precision,  accuracy and types of errors, Sample, Population, Mean, Average, Median, Range, Standard  Deviation, Variance, Significant figures, Chemical Equilibrium ant its types.  Separation Techniques: Chromatography (Introduction, Classification.)  TLC. Column & Ion exchange chromatography (with reference to principles & applications). Electrophoresis & Solvent Extraction. 

                                            WEEKLY LECTURE SCHEDULE*

* Class of Ex-PPP was started one week late and will end by May 15, 2020 accordingly

RESEARCH PROJECT AND PRACTICALS

Presentation on different Research Topics as a part of assignment

PRACTICALS

1. Calibration of glass ware (Pipette, Burette, Flask) used for volumetric Analysis.
2. Use of Analytical balance and calculation of standard deviation.
3. Use of pH meter for plotting acid - base titration curve and assay of commercial caustic soda.
4. Plotting of first differential curve for titration of acetic acid and commercial soda.
5. Measurement of solubility products of sparingly soluble salts.
6. Determination of HCl by titrating with NaOH and plotting of a titration curve.
7. Packing of chromatographic column and separation of mixture of dyes.
8. Separation of various components of plant extract by column chromatography.
9. Separation of mixture of dyes by Radial chromatography.
10. Separation of mixture of Amino acids by paper chromatography.
11. Coating of TLC plates and separation of mixture of dyes.
12. Separation of mixture of Amino acids by TLC.

ASSESSMENT CRITERIAITERIA

Mid Term Exam: 15%

Sessional:  15%

Practical work: 25%

Presentation:  Included in sessional marks

Participation:  Included in sessional marks

Final exam: 45%

RULES AND REGULATIONS

1. Minimum attendance 75% is necessary to appear in exam.
2. Keep your mobiles off/silent during class time.