Course title: Blood Chemistry and Immunology

Course code: CHEM 7155

Credit Hours: 03

Instructor: Dr. Sobia Noreen

Email: [email protected]

Course objectives:

This course describes the basic concepts blood chemistry specifically the principles and procedures of various tests performed in blood Chemistry, Physiological basis, and clinical significance of test results, Basic biochemical laboratory techniques and safety etc. Present course will also enable the students to understand the field of immunology with emphasis on the biochemical aspects of the systems. Immunology, in the broadest sense, is the study of how our bodies deal with non-self entities with which we come in contact. This includes foreign molecules, bacteria, fungi, viruses, allergens, microbes, and even tumors.

COURSE SCHEDULE

Learning outcomes and Course contents:

This course is designed to broaden the student's outlook and deepen his interest in everything that concerns blood chemistry and immunology. In this course, the students will also be exposed briefly to certain specific areas related to the principles and procedures of various tests performed in blood Chemistry, Physiological basis, and clinical significance of test results, Basic biochemical laboratory techniques and safety, Analysis of electrolytes, acid-base balance, proteins, carbohydrates, lipids, enzymes, endocrine function, and toxicology, Introduction to different types of ELISA;  Fundamentals of immune system; elements of innate and acquired immunity, immunogens and antigens, antibody structure and function; antigen-antibody interactions; genetic basis of antibody structure; monoclonal antibodies; biology of the B lymphocytes, role of MHC in the immune system; biology of the T lymphocyte; activation and function of T and B cells; control mechanisms in immune response, cytokines, complement, hypersensitivity reactions; type I, II, III, IV, autoimmunity; resistance and immunization to infectious diseases; applications of immunological functions.

READINGS

1.Kindt T.J, Osborne B.A, and Golds R.A., Kuby Immunology, W. H. 6th Ed. (2006).

2.Paul, W.E. Fundamental Immunology, 6th Ed. Lippincott Williams & Wilkins. (2008).

3.Murphy K.M. Travers P., and Walport M., Immunobiology, 7th Ed. Garland Science (2007).

4.Coico, R. Immunology: A Short Course, 6th Ed., Wiley-Blackwell (2009).

5.Van, C. J., van-Reganmortel M. H. V., and Dekker M. Immunochemistry, New York (1994).

6.Sompayrac L.M. How the Immune System Works, 3rd Wiley-Blackwell Publishers, NY (2008).

7.DeHaan M.R. Chemistry of the Blood, Zondervan Publishers, Paris (1983).

8.Tips, J. Blood Chemistry & Clinical Nutrition, Apple-a-Day Press, UK (2007).

ASSESMENT CRITERIA

Midterm: 30%

Sessional: 20%

Project: 15%

Presentation: 10%

Viva: 25%

RULES AND REGULATIONS

Following are the rules and regulations that students have to abide by in my class

1. Class attendance. (80% class attendance)
2. Study of course materials as specified by the instructor
3. Completion of given task on time